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Information about Proquin XR
ProquinXR Tough on the infection, gentle on your stomach

SUBSTITUTION NOT ALLOWED

  • NOT interchangeable with Cipro® or Cipro® XR
  • NO AB-rated generic equivalents
  • Only once-daily ciprofloxacin that contains ciprofloxacin hydrochloride as a single source ingredient.*4

* Proquin XR contains a single active ingredient, ciprofloxacin hydrochloride. Cipro XR (ciprofloxacin extended-release tablets) contains two different ciprofloxacin salts — ciprofloxacin hydrochloride and ciprofloxacin betaine.

The Novel Prolonged-release Quinolone

  • Significant reduction of nausea and diarrhea vs Cipro1,2
  • Proven efficacy — 93.4% eradication rate vs 89.6% for Cipro2
  • Once-daily dosing — 500 mg tablets1
  • Unlike Cipro XR, no drug — drug interaction with Prilosec®1,3
Important Safety Information
Adverse reactions determined to be at least possibly drug-related occurring in greater than or equal to 1% of patients were fungal infections (1.6%).
Proquin® XR tablets should be taken whole and never split, crushed, or chewed. Proquin® XR should be taken with the main meal of the day. Proquin® XR is not interchangeable with other ciprofloxacin extended-release (Cipro® XR) or immediate-release (Cipro®) oral formulations.

Proquin XR should be administered at least 4 hours before or 2 hours after antacids containing magnesium or aluminum, sucralfate, VIDEX ® (didanosine) chewable/buffered tablets or pediatric powder, metal cations such as iron, and multivitamin preparations containing zinc.

The safety and effectiveness of Proquin® XR in children, adolescents less than 18 years of age, pregnant women and lactating women have not been established. Proquin® XR is contraindicated in persons with a history of hypersensitivity to ciprofloxacin or any quinolone, and should be discontinued at the first sign of an allergic reaction.

Serious and fatal reactions have been reported in patients receiving concurrent administration of ciprofloxacin and theophylline. Monitor theophylline levels if concurrent administration cannot be avoided.

Please see full Prescribing Information including black box warning regarding tendon ruptures.